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Antigenic Specificity | APPL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008] |
Immunogen | Immunogen: Rabbit polyclonal APPL1 (1) antibody was raised against a recombinate human APPL1 protein 502-681aa (BC028599). |
Other Names | [adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1], [appl1; appl; dip13alpha] |
Gene, Accession # | [APPL1], Gene ID: 398984, NCBI: NP_001083546.1 |
Catalog # | MBS416077 |
Price | $230 |
Order / More Info | APPL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Lee,J.R., Hahn,H.S., Kim,Y.H. et al. Adaptor protein containing PH domain, PTB domain and leucine zipper (APPL1) regulates the protein level of EGFR by modulating its trafficking. Biochem. Biophys. Res. Commun. 415 (1), 206-211 (2011). |