Mouse Foxp3 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Mouse Foxp3 antibody, protein, ELISA kits.
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| Antigenic Specificity | Mouse Foxp3 |
| Clone | polyclonal |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Mouse Foxp3 (Mr ~57 kDa). Does not cross react with Human Foxp3. T regulatory cells (Originally called T suppressor cells) are a subpopulation of T cells. Their major roles are to suppress excess immune response of other cells and to maintain tolerance of self-antigens. Initially, researchers used CD4 and CD25 (IL-2 receptor) to identify T suppress subpopulation and purified CD4+CD25+ T cells were used for T cells Suppression Assay, however some other activated T cells also express CD25.1,2 The most convincible molecular marker of Treg cells is Forkhead box protein 3 (Foxp3) which is expressed in the nucleus.3 Anti-Foxp3 antibodies are now widely applied to identify the roles of Treg cells in the development of many diseases, s |
| Immunogen | Immunogen: N-terminal recombinant Mouse Foxp3. Characterization: To insure acceptable performance, each batch of product is tested by flow cytometry to conform to characteristics of a standard reference reagent. Representative flow data are included in this product insert |
| Other Names | [forkhead box protein P3 isoform b; Forkhead box protein P3; forkhead box protein P3; scurfin; FOXP3delta7; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; forkhead box P3; Scurfin], [FOXP3; FOXP3; JM2; AIID; IPEX; PIDX; XPID; DIETER; IPEX] |
| Gene, Accession # | Gene ID: 50943, NCBI: NP_001107849.1, UniProt: Q9BZS1 |
| Catalog # | MBS670395 |
| Price | $350 |
| Order / More Info | Mouse Foxp3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Fehervari Z, Sakaguchi S. Development and function of CD25 CD4 regulatory T cells. Curr Opin Immunol. 2004 Apr; 16(2):203-8. Review. 2. Gallimore A, Sakaguchi S. Regulation of tumor immunity by CD25 T cells. Immunology. 2002 Sep; 107(1):5-9. Review. 3. Zhang L, Zhao Y (June 2007). The regulation of Foxp3 expression in regulatory CD4( )CD25( )T cells: multiple pathways on the road. J. Cell. Physiol. 211 (3): 590-597. 4. Sakaguchi S, Sakaguchi N, Shimizu J, Yamazaki S, Sakihama T, Itoh M, Kuniyasu Y, Nomura T, Toda M, Takahashi T. Immunologic tolerance maintained by CD25 CD4 regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev. 2001 Aug; 182:18-32 5. Elkord E, Alcantar-Orozco EM, Dovedi SJ, Tran DQ, Hawkins RE, Gilham DE. T regulatory cells in cancer: recent advances and therapeutic potential. Expert Opin Biol Ther. 2010 Nov; 10(11):1573-86. 6. FOXP3( ) regulatory T cells: From suppression of rejection to induction of renal allograft tolerance. Dummer CD, Carpio VN, Goncalves LF, Manfro RC, Veronese FV. Transpl Immunol. 2011 Sep 13. 7. Horwitz DA. Identity of mysterious CD4 CD25-Foxp3 cells in SLE. Arthritis Res Ther 2010;12(1):101 8. Bovenschen HJ, van de Kerkhof PC, van Erp PE, Woestenenk R, Joosten I, Koenen HJ. Foxp3 regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin. J Invest Dermatol. 2011 Sep; 131(9):1853-60 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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