CTNNB1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CTNNB1 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | CTNNB1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | beta-Catenin is a key downstream effector in the Wnt signaling pathway (1). It is implicated in two major biological processes in vertebrates: early embryonic development (2) and tumorigenesis (3). CK1 phosphorylates beta-catenin at Ser45. This phosphorylation event primes beta-catenin for subsequent phosphorylation by GSK-3beta (4-6). GSK-3beta destabilizes beta-catenin by phosphorylating it at Ser33, Ser37, and Thr41 (7). Mutations at these sites result in the stabilization of beta-catenin protein levels and have been found in many tumor cell lines (8). |
| Immunogen | Immunogen: A synthetic peptide of human CTNNB1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [CTNNB; DKFZp686D02253; FLJ25606; FLJ37923; beta-catenin] |
| Gene, Accession # | [CTNNB1], Gene ID: 1499, NCBI: NP_001091679.1, UniProt: P35222 |
| Catalog # | MBS8503406 |
| Price | $310 |
| Order / More Info | CTNNB1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Cadigan, K.M. and Nusse, R. (1997) Genes Dev. 11, 3286-3305. 2. Wodarz, A. and Nusse, R. (1998) Annu. Rev. Cell. Dev. Biol. 14, 59-88. 3. Polakis, P. (1999) Curr. Opin. Genet. Dev. 9, 15-21. 4. Amit, S. et al. (2002) Genes Dev. 16, 1066-1076. 5. Lin, C. et al. (2002) Cell 108, 837-847. 6. Yanagawa, S. et al. (2002) EMBO J. 21, 1733-1742. 7. Yost, C. et al. (1996) Genes Dev. 10, 1443-1454. 8. Morin, P.J. (1997) Science 275, 1787-1790. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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