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Antigenic Specificity | SOCS4 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Suppressor of cytokine signaling 4(SOCS4) detection. Tested with WB in Human. Background: SOCS4, also known as Suppressor of cytokine signaling 4, is mapped to 14q22.1. The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. |
Immunogen | Immunogen: E Coli-derived human SOCS4 recombinant protein (Position: M291-C440). Human SOCS4 shares 98% amino acid (aa) sequence identity with mouse SOCS4. Ig Type: Rabbit IgG |
Other Names | [Suppressor of cytokine signaling 4; CIS4; Cish4; Cytokine inducible SH2 protein 4; DKFZp686J1568; HSPC060; SH2 domain containing SOCS box protein; SOCS-4; SOCS-7; SOCS4; SOCS4_HUMAN; SOCS6; SOCS7; SSI4; STAI4; STAT induced STAT inhibitor 4; STAT4; STATI4; Suppressor of cytokine signaling 4; Suppressor of cytokine signaling 7; suppressor of cytokine signaling 4], [SOCS4; SOCS4; SOCS7; SOCS7; SOCS-4; SOCS-7] |
Gene, Accession # | [SOCS4], Gene ID: 122809, NCBI: NP_543143.1, UniProt: Q8WXH5 |
Catalog # | MBS177811 |
Price | $280 |
Order / More Info | SOCS4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Bullock AN; Rodriguez MC; Debreczeni JE; Songyang Z; Knapp S. Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation. Structure, 2007 Nov. 2. Kobayashi D; Nomoto S; Kodera Y; Fujiwara M; Koike M; Nakayama G; Ohashi N; Nakao A. Suppressor of cytokine signaling 4 detected as a novel gastric cancer suppressor gene using double combination array analysis. World J Surg, 2012 Feb. |