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Antigenic Specificity | GCK/GLK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of GCK/GLK. The protein encoded by MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human GCK/GLK protein at amino acid sequence of 221-270 |
Other Names | [Rabbit GCK/GLK; Mitogen-activated protein kinase kinase kinase kinase 2; B lymphocyte serine/threonine-protein kinase; Germinal center kinase; GC kinase; MAPK/ERK kinase kinase kinase 2; MEK kinase kinase 2; MEKKK 2; Rab8-interacting protein Mitogen-activated protein kinase kinase kinase kinase 3; Germinal center kinase-related protein kinase; GLK; MAPK/ERK kinase kinase kinase 3; MEK kinase kinase 3; MEKKK 3] |
Gene, Accession # | [GCK/GLK], Gene ID: 5871, NCBI: NP_004570.2, UniProt: Q12851 |
Catalog # | MBS9709196 |
Price | $130, $220, $325 |
Order / More Info | GCK/GLK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |