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Antigenic Specificity | RALA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transfor |
Immunogen | Immunogen: Recombinant Human Ras-related protein Ral-A protein (1-203AA) |
Other Names | [Ras-related protein Ral-A; RALA; RAL] |
Gene, Accession # | [RALA], Gene ID: 5898, NCBI: NP_005393.2, UniProt: P11233 |
Catalog # | MBS7105085 |
Price | $160, $235 |
Order / More Info | RALA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |