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Antigenic Specificity | CD79A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to CD79A. Antigen receptors found on the surface of B-cells contain a hetrodimeric signaling component composed of CD79A and CD79B, also known as Ig alpha and Ig beta, respectively (1,2). Presence of this receptor complex is essential for B-cell development and function (3). Together these two proteins and the associated B cell receptor initiate intracellular signaling following antigen binding (4,5). An immunoreceptor tyrosine-based activation motif (ITAM) is found in the CD79A intracellular region appears to be is important for its function (6). Antigen binding precedes formation of the CD79A and CD79B heterodimer and subsequent activation of receptor associated kinases (7). CD79A is a marker for B-lineage lymphoblastic |
Immunogen | Immunogen: A synthetic -peptide of human CD79A |
Other Names | [CD79A; IGA, MB1], [CD79A; CD79A; IGA; MB-1; IGA; MB1] |
Gene, Accession # | Gene ID: 973, NCBI: NP_001774.1, UniProt: P11912 |
Catalog # | MBS126003 |
Price | $200, $275, $430 |
Order / More Info | CD79A Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. van Noesel, C.J. et al. (1991) J Immunol 146, 3881-8. 2. Minegishi, Y. et al. (1999) J Clin Invest 104, 1115-21. 3. Yu, L.M. and Chang, T.W. (1992) J Immunol 148, 633-7. 4. Storch, B. et al. (2007) Eur J Immunol 37, 252-60. 5. Mason, D.Y. et al. (1995) Blood 86, 1453-9. 6. Luisiri, P. et al. (1996) J Biol Chem 271, 5158-63. 7. Pike, K.A. et al. (2004) J Immunol 172, 2210-8. 8. Astsaturov, I.A. et al. (1996) Leukemia 10, 769-73. 9. Vuillier, F. et al. (2005) Blood 105, 2933-40. |