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Antigenic Specificity | Human Proteasome subunit alpha type-7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increase |
Immunogen | Immunogen: Recombinant human Proteasome subunit alpha type-7 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54728 / sc-67344 |
Other Names | [HSPC; PSMA7; Proteasome subunit RC6-1 Proteasome subunit XAPC7], [PSMA7; PSMA7; C6; HSPC; RC6-1; XAPC7; HEL-S-276; HSPC] |
Gene, Accession # | Gene ID: 5688, NCBI: NP_002783.1, UniProt: O14818 |
Catalog # | MBS715025 |
Price | $160, $235 |
Order / More Info | Human Proteasome subunit alpha type-7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |