Desmin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDesmin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe cytoskeleton consists of three types of cytosolic fibers: microfilaments (actin filaments), intermediate filaments and microtubules. Major types of intermediate filaments are distinguished and expressed in particular cell types: cytokeratins (epithelial cells), glial fibrillary acidic protein or GFAP (glial cells), desmin (skeletal, visceral and certain vascular smooth muscle cells), vimentin (mesenchyme origin) and neurofilaments (neurons). GFAP and vimentin form intermediate filaments in astroglial cells and modulate their motility and shape (1). In particular, vimentin filaments are present at early developmental stages, while GFAP filaments are characteristic of differentiated and mature brain astrocytes. Thus, GFAP is commonly used
ImmunogenImmunogen: Fusion protein of human DES Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[CMD1I; CSM1; CSM2; FLJ12025; FLJ39719; FLJ41013; FLJ41793; Desmin]
Gene, Accession #[DES], Gene ID: 1674, NCBI: NP_001918.3, UniProt: P17661
Catalog #MBS8504268
Price$310
Order / More InfoDesmin Antibody from MYBIOSOURCE INC.
Product Specific References1. Eng, L.F. et al. (2000) Neurochem Res 25, 1439-51. 2. Goebel, H.H. et al. (1987) Acta Histochem Suppl 34, 81-93. 3. Leader, M. et al. (1987) Histopathology 11, 63-72. 4. Capetanaki, Y. et al. (2007) Exp Cell Res 313, 2063-76. 5. Li, Z. et al. (1996) Dev Biol 175, 362-6. 6. Paulin, D. and Li, Z. (2004) Exp Cell Res 301, 1-7. 7. Paulin, D. et al. (2004) J Pathol 204, 418-27.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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