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Antigenic Specificity | Phospho-PBK/TOPK (Thr9) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Phospho-PBK/TOPK (Thr9) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-35 amino acids from the human Phospho-PBK/TOPK. Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. |
Immunogen | n/a |
Other Names | [Lymphokine-activated killer T-cell-originated protein kinase; 2.7.12.2; Cancer/testis antigen 84; CT84; MAPKK-like protein kinase; Nori-3; PDZ-binding kinase; Spermatogenesis-related protein kinase; SPK; T-LAK cell-originated protein kinase; PBK; TOPK] |
Gene, Accession # | [PBK], Gene ID: 55872, NCBI: NP_001265874.1, UniProt: Q96KB5 |
Catalog # | MBS9231103 |
Price | $165, $370 |
Order / More Info | Phospho-PBK/TOPK (Thr9) Antibody from MYBIOSOURCE INC. |
Product Specific References | Abe Y.,et al.J. Biol. Chem. 275:21525-21531 (2000). Gaudet S.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:5167-5172 (2000). Zhao S.,et al.Int. J. Biochem. Cell Biol. 33:631-636 (2001). Ota T.,et al.Nat. Genet. 36:40-45 (2004). Nusbaum C.,et al.Nature 439:331-335 (2006). |