TRAF4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRAF4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: TRAF4 antibody detects endogenous levels of total TRAF4. Function: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.Subunit Structure: Homotrimer (Probable). Interacts with LTBR/TNFRSF3, NGFR/TNFRSF16, RPS6KB1 and TGFB1I1. Interacts with SMU
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cytoplasm. Nucleus. Cytoplasm > Perinuclear Region. Cell Junction > Tight Junction. Cell Membrane. Cytoplasm > Cytoskeleton. Tissue Specificity: Expressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit Similarit
Other Names[CART 1; CART1; cysteine rich domain associated with ring and TRAF domain; Cysteine rich domain associated with RING and Traf domains protein 1; Cysteine-rich domain associated with RING and Traf domains protein 1; Malignant 62; Metastatic lymph node gene 62 protein; MLN 62; MLN62; RING finger protein 83; RNF 83; RNF83; TNF receptor associated factor 4; TNF receptor-associated factor 4; TRAF 4; Traf4; TRAF4_HUMAN; tumor necrosis receptor-associated factor 4A]
Gene, Accession #[TRAF4], Gene ID: 9618, NCBI: NP_004286.2, UniProt: Q9BUZ4
Catalog #MBS9606182
Price$240, $280
Order / More InfoTRAF4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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