CDK5R1 (N-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CDK5R1 (N-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL |
| Concentration | vial concentration: 0.309 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CDK5R1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 30-64 amino acids from the N-terminal region of human CDK5R1. p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution. |
| Immunogen | n/a |
| Other Names | [Cyclin-dependent kinase 5 activator 1; CDK5 activator 1; Cyclin-dependent kinase 5 regulatory subunit 1; TPKII regulatory subunit; Cyclin-dependent kinase 5 activator 1; p35; p35; Cyclin-dependent kinase 5 activator 1; p25; p25; Tau protein kinase II 23 kDa subunit; p23; CDK5R1; CDK5R; NCK5A] |
| Gene, Accession # | [CDK5R1], Gene ID: 8851, NCBI: NP_003876.1, UniProt: Q15078 |
| Catalog # | MBS9213336 |
| Price | $150 |
| Order / More Info | CDK5R1 (N-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Tsai L.-H.,et al.Nature 371:419-423(1994). Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Patrick G.N.,et al.Nature 402:615-622(1999). Kerokoski P.,et al.Brain Res. Mol. Brain Res. 106:50-56(2002). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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