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Antigenic Specificity | AGK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AGK antibody detects endogenous levels of total AGK. Function: Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively (PubMed:15939762). Does not phosphorylate sphingosine (PubMed:15939762). Independently of its lipid kinase activity, acts as a component of the TIM22 complex (PubMed:28712724, PubMed:28712726). The TIM22 complex mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane by forming a twin-pore translocase that uses the membrane potential as the external driving force (PubMed:28712724, PubMed:28712726). In the TIM22 complex, required for the import of a subset of meta |
Immunogen | Immunogen: A synthesized peptide derived from human AGK Subcellular Location: Mitochondrion Membrane. Tissue Specificity: Highly expressed in muscle, heart, kidney and brain. Predicted Cross Reactivity: Bovine, Dog, Chicken Similarity: Bovine (88%), Dog (88%), Chicken (88%) |
Other Names | [2610037M15Rik; 6720408I04Rik; Acylglycerol kinase mitochondrial; Acylglycerol kinase, mitochondrial; agk; AGK_HUMAN; AI465370; FLJ10842; hAGK; HsMuLK; MuLK; Multi substrate lipid kinase; Multi-substrate lipid kinase; Multiple substrate lipid kinase; RGD1562046] |
Gene, Accession # | [AGK], Gene ID: 55750, NCBI: NP_060708.1, UniProt: Q53H12 |
Catalog # | MBS9609152 |
Price | $240, $280 |
Order / More Info | AGK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |