Phospho-PSD95 (Ser295) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Phospho-PSD95 (Ser295) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Phospho-PSD95 (Ser295) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-PSD95 (Ser295) antibody detects endogenous levels of PSD95. Function: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression.Subunit Structure: I |
| Immunogen | Immunogen: A synthesized peptide derived from human PSD95 around the phosphorylation site of Ser295. Subcellular Location: Cell Membrane. Cell Junction, Synapse, Postsynaptic Cell Membrane, Postsynaptic Density. Cell Projection, Axon. Cell Junction, Synapse. High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of purkinje cells. Tissue Specificity: Brain. Predicted Cross Reactivity: P |
| Other Names | [Discs large homolog 4; Disks large homolog 4; DLG 4; Dlg4; DLG4_HUMAN; FLJ97752; FLJ98574; Human post synaptic density protein 95; Post synaptic density protein 95; Postsynaptic density protein 95; PSD 95; PSD-95; PSD95; SAP 90; SAP-90; SAP90; Synapse associated protein 90; Synapse-associated protein 90; Tax interaction protein 15] |
| Gene, Accession # | [PSD95], Gene ID: 1742, NCBI: NP_001122299.1, UniProt: P78352 |
| Catalog # | MBS9600718 |
| Price | $240, $280 |
| Order / More Info | Phospho-PSD95 (Ser295) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies