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Antigenic Specificity | Glutamate GluR3 |
Clone | [Glu149.29.61] |
Host Species | Mouse |
Reactive Species | human, porcine, rat |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody the extracellular domain of Glu3RB (aa 372 to 395). Glutamate is the main excitatory neurotransmitter in the mammalian central nervous system (CNS). Its receptors are either metabotropic or ionotropic. The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor, also known as the AMPA receptor, is an ionotropic receptor made up of homomeric or heteromeric arrangments of Glutamate Receptor (GluR) subunits 1 to 4. GluR3 is one of the most common AMPA receptor in the CNS. The receptors are localized mainly post-synaptically and play important roles in the development and function of the nervous system. Autoimmunity to glutamate receptors may contribute to the pathology of some epilepsy syndromes. |
Immunogen | Immunogen: aa372-395 |
Other Names | n/a |
Gene, Accession # | [GluR3] |
Catalog # | MBS588026 |
Price | $435 |
Order / More Info | Glutamate GluR3 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Cohen-Kashi Malina K-Autoantibodies against an extracellular peptide of the GluR3 subtype of AMPA receptors activate both homomeric and heteromeric AMPA receptor channels. |