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Antigenic Specificity | Human SESN3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Sestrins, including sestrin-1 (PA26), sestrin-2 (Hi95), and sestrin-3, are 48 to 65 kDa cystein sulfinyl reductases and they modulate peroxide signaling and antioxidant defense. These proteins selectively reduce or repair hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. Expression of these proteins is regulated by p53, a tumor suppressor protein. Sestrin 3 was identified as a forkhead box O (FoxO) target gene with antioxidant activity. |
Immunogen | Immunogen: Recombinant human Sestrin-3 protein (1-310aa) |
Other Names | [SESN3;SEST3], [SESN3; SESN3; SEST3; SEST3] |
Gene, Accession # | [SESN3], Gene ID: 143686, NCBI: NP_001258523.1, UniProt: P58005 |
Catalog # | MBS1499970 |
Price | $120, $160 |
Order / More Info | Human SESN3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |