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Antigenic Specificity | ZCHC8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of ZCHC8 protein. ZCCHC8 (Zinc Finger CCHC-Type Containing 8) is a Protein Coding gene. ZCCHC8 encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal |
Immunogen | Immunogen: Synthesized peptide derived from part region of human ZCHC8 protein |
Other Names | [Rabbit ZCHC8; Zinc finger CCHC domain-containing protein 8; TRAMP-like complex RNA-binding factor ZCCHC8] |
Gene, Accession # | [ZCHC8], Gene ID: 55596, NCBI: NP_060082.2, UniProt: Q6NZY4 |
Catalog # | MBS9711478 |
Price | $130, $220, $325 |
Order / More Info | ZCHC8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |