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Antigenic Specificity | Human CD61 |
Clone | [VI-PL2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | fluorescein (FITC) conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD61, also known as integrin beta3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin alphaV (CD51) to form alphaV/beta3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins. |
Immunogen | n/a |
Other Names | [GP3A; GPIIIa; ITGB3; Integrin beta-3] |
Gene, Accession # | [CD61], Gene ID: 3690, NCBI: NP_000203.2, UniProt: P05106 |
Catalog # | MBS2559177 |
Price | $100, $125, $165 |
Order / More Info | Human CD61 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |