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Antigenic Specificity | CaV3.1 |
Clone | [S178A-9] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | PerCP conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects ~>200kDa. Does not cross-react with Cav3.2 Scientific Background: Calcium channel CaV3.1 (a1G) is a low-voltage-activated T-type calcium channel. Such T-type channels are expressed throughout the body. In the heart, they may be involved in pacemaker current. In neurons, these channels may play a secondary pacemaker role (3). With the ubiquitous expression, it is not surprising that alterations in channel function have been implicated in disease. Drugs that act to block T-type calcium channels are used as anti-hypertensives, antiepileptic's, and blocking of T-type calcium channels may be involved in the action of some anesthetics and antipsychotics as well (3). Much remains to be determined about the precise cellular |
Immunogen | n/a |
Other Names | [CACNA1G; CaV T1; Cav3 1; cav3 1c; KIAA1123; MGC117234; NBR13; voltage gated calcium channel cav3.1; calcium channel voltage dependent alpha 1G subunit; calcium channel voltage dependent T type alpha 1G subunit; calcium channel], [Cacna1g; Cacna1g; a1G; [a]1G; Cav3.1d; alpha-1G; mKIAA1123] |
Gene, Accession # | Gene ID: 12291, NCBI: NP_001106284.1, UniProt: Q9WUT2 |
Catalog # | MBS800392 |
Price | $435 |
Order / More Info | CaV3.1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.:Sunderland, MA USA. 2. www.iochannels.org 3. Perez-Reyes E. (2003). Physiol. Rev., 83: 117-161. |