Phospho-AKT1 (S473) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-AKT1 (S473) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), Dot Blot (DB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Phospho-AKT1-pS473 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S473 of human AKT1. The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transc |
| Immunogen | n/a |
| Other Names | [RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; AKT1; PKB; RAC] |
| Gene, Accession # | [AKT1], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749 |
| Catalog # | MBS9208927 |
| Price | $165, $370 |
| Order / More Info | Phospho-AKT1 (S473) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Liao, Y., et al., Int. J. Cancer 107(4):676-680 (2003). Powell, D.J., et al., Mol. Cell. Biol. 23(21):7794-7808 (2003). Debnath, J., et al., J. Cell Biol. 163(2):315-326 (2003). Li, G., et al., Oncogene 22(44):6891-6899 (2003). Liao, Y., et al., Mol. Cell. Biol. 23(19):6836-6848 (2003). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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