Phospho-PAK4/PAK5/PAK6 (S474/S560/S602) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-PAK4/PAK5/PAK6 (S474/S560/S602)
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formataffinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
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DescriptionSerine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, growth, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates LIMK1, a kinase that also inhibits the activity of cofilin. Phosphorylates integrin beta5/ITGB5 and thus re
ImmunogenImmunogen: A synthesized peptide derived from human Phospho-PAK4/PAK5/PAK6 (S474/S560/S602)
Other Names[Serine/threonine-protein kinase PAK 4; p21-activated kinase 4; PAK-4; PAK4; KIAA1142]
Gene, Accession #[PAK4/PAK5/PAK6], Gene ID: 10298, NCBI: NP_001014831.1, UniProt: O96013
Catalog #MBS7114875
Price$185, $265
Order / More InfoPhospho-PAK4/PAK5/PAK6 (S474/S560/S602) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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