PPP1R16B Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PPP1R16B |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PPP1R16B antibody detects endogenous levels of total PPP1R16B. Function: Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function (PubMed:18586956). Involved in the regulation of the PI3K/AKT signaling pathway, angiogenesis and endothelial cell proliferation (PubMed:25007873). Regulates angiogenesis and endothelial cell proliferation through the control of ECE1 dephosphorylation, trafficking and activity (By similarity). Protects the endothelial barrier from lipopolysaccharide (LPS)-induced vascular leakage (By similarity). Involved in the regulation of endothelial cell filopodia extension (By similarity). May be a downstream target for TGF-beta1 signaling ca |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus; Plasma Membrane Tissue Specificity: Inhibited by TGFB1 (Probable). Down-regulated by LPS (PubMed:21907835). Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (94%), Zebrafish (80%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (93%), Dog (88%) |
| Other Names | [ANKRD4; Ankyrin repeat domain containing protein 4; ankyrin repeat domain protein 4; Ankyrin repeat domain-containing protein 4; CAAX box protein TIMAP; hTIMAP; KIAA0823; PP16B_HUMAN; PPP1R16B; Protein phosphatase 1 regulatory inhibitor subunit 16B; protein phosphatase 1, regulatory (inhibitor) subunit 16B; TGF beta inhibited membrane associated protein; TGF-beta-inhibited membrane-associated protein; TIMAP] |
| Gene, Accession # | [PPP1R16B], Gene ID: 26051, NCBI: NP_001166206.1, UniProt: Q96T49 |
| Catalog # | MBS9605796 |
| Price | $240, $280 |
| Order / More Info | PPP1R16B Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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