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Antigenic Specificity | DOT1L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DOT1L antibody detects endogenous levels of total DOT1L. Function: Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.Subunit Structure: Interacts with MLLT10.Similarity: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Predicted Cross Reactivity: Bovine, Sheep Similarity: Bovine (90%), Sheep (90%) |
Other Names | [Disrupter of telomere silencing protein 1; DOT 1; DOT1; DOT1 like; DOT1 like histone H3 methyltransferase (S. cerevisiae); DOT1 like histone H3 methyltransferase; DOT1 like histone H3K79 methyltransferase; DOT1 like protein; DOT1, S. cerevisiae, homolog of; DOT1-like protein; DOT1L; DOT1L_HUMAN; EC 2.1.1.43; H3 K79 HMTase; H3 lysine-79 specific; H3-K79-HMTase; Histone H3 K79 methyltransferase; Histone H3 methyltransferase; Histone H3 methyltransferase DOT1-like; Histone H3-K79 methyltransferase; Histone lysine N methyltransferase H3 lysine 79 specific; Histone methyltransferase DOT1L; Histone-lysine N-methyltransferase; KIAA1814; KMT4; Lysine N methyltransferase 4; Lysine N-methyltransferase 4] |
Gene, Accession # | [DOT1L], Gene ID: 84444, NCBI: NP_115871.1, UniProt: Q8TEK3 |
Catalog # | MBS9604004 |
Price | $240, $280 |
Order / More Info | DOT1L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |