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Antigenic Specificity | IRF4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3' ), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 150-350 of human IRF4 (NP 002451.2). |
Other Names | [MUM1; LSIRF; SHEP8; NF-EM5] |
Gene, Accession # | [IRF4], Gene ID: 3662, NCBI: NP_001182215.1, UniProt: Q15306 |
Catalog # | MBS8544047 |
Price | $280 |
Order / More Info | IRF4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |