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Antigenic Specificity | FOXA3/HNF3G |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | Size: 100 ug/200 ul |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes ~37 kDa of FOXA3 protein. It also reacts with human, mouse and rat. The other species are not tested. The forkhead box gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA1 plays an important role in breast cancer. The FOXA subfamily is composed of the transcription factors FOXA1, A2, A3. They were discovered as the regulators of hepatic genes. Foxa1 has been shown to be required for glucagon secretion i |
Immunogen | Antigen Preparation: A synthetic peptide corresponding to the C-terminus of human FOXA3 protein. This sequence is identical to rat, mouse and human origins. |
Other Names | [Rabbit FOXA3; Forkhead Box A2 (FOXA3); Hepatocyte nuclear factor 3 gamma (HNF3G)], [FOXA3; FOXA3; FKHH3; HNF3G; TCF3G; MGC10179; HNF3G; TCF3G] |
Gene, Accession # | [FOXA3], Gene ID: 3171, UniProt: P55318 |
Catalog # | MBS462181 |
Price | $285 |
Order / More Info | FOXA3/HNF3G Antibody from MYBIOSOURCE INC. |
Product Specific References | Shen W et al. Foxa3 (hepatocyte nuclear factor 3gamma) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast. 2001 Nov 16;276 (46):42812-7. |