GSK3alpha (Phospho-Ser21) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | GSK3alpha (Phospho-Ser21) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects endogenous human, mouse, and rat GSK3alpha only when phosphorylated at serine 21 and does not detect GSK3beta phosphorylated at Ser9. GSK3 acts as a multifunctional downstream switch that determines the output of numerous signaling pathways. There are two mammalian GSK-3 isoforms encoded by distinct genes, GSK3 alpha and GSK3 beta, which are structurally similar, but functionally non-identical. GSK3alpha is inhibited by phosphorylation at S21 by Akt and other kinases. Dysregulated GSK3 has been implicated in several diseases including type II diabetes, Alzheimers disease, and cancer. |
| Immunogen | Antigen: Peptide sequence that includes phosphorylation site of serine 21 (T-S-S(p)-F-A) derived from human GSK3alpha and conjugated to KLH. |
| Other Names | [glycogen synthase kinase-3 alpha; Glycogen synthase kinase-3 alpha; glycogen synthase kinase-3 alpha; glycogen synthase kinase 3 alpha; Serine/threonine-protein kinase GSK3A (EC:2.7.11.1)], [GSK3A; GSK3A; GSK-3 alpha] |
| Gene, Accession # | [GSK3alpha], Gene ID: 2931, NCBI: NP_063937.2, UniProt: P49840 |
| Catalog # | MBS191019 |
| Price | $340 |
| Order / More Info | GSK3alpha (Phospho-Ser21) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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