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Antigenic Specificity | Cathepsin D |
Clone | [4G2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The aspartic protease cathepsin D is one of the major proteolytic enzymes in lysosomes. The cathepsin D gene locates on chromosome 11p15.5 and spans approximately 11 kb with nine exons. Initially synthesized as an inactive precursor of pro-cathepsin D, the enzyme is subsequently converted to its active forms by proteolytic processing. Breast cancer cells, unlike normal cells, secrete high levels of pro-cathepsin D |
Immunogen | Immunogen: Recombinant human Cathepsin D (21-412 aa) purified from E. coli |
Other Names | [CTSD,CPSD; CLN10; MGC2311; cathepsin D; cathepsin D (lysosomal aspartyl protease); ceroid-lipofuscinosis; neuronal 10], [CTSD; CTSD; CPSD; CLN10; HEL-S-130P; CPSD] |
Gene, Accession # | Gene ID: 1509, NCBI: NP_001900, UniProt: P07339 |
Catalog # | MBS200038 |
Price | $240, $315 |
Order / More Info | Cathepsin D Antibody from MYBIOSOURCE INC. |
Product Specific References | Tang,J. (1979) Mol. Cell. Biochem. 26, 93-109; Fujita, H et al., (1991) Biochem. Biophys. Res. Commun. 179, 190-196; Fusek, M et al., (2005) Biomed Papers 149, 43-50; Garcia,M et al., (1996) Stem Cells 14, 642-650 |