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Antigenic Specificity | BRCAA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BRCAA1 antibody detects endogenous levels of total BRCAA1. Function: Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.Subunit Structure: Component of a Sin3A corepressor complex consisting of SIN3A, SAP130, SUDS3/SAP45, SAP180, HDAC1 and HDAC2.Similarity: The C-terminus mediates interaction with mSin3A corepressor complex.The N-terminus is involved in transcriptional repression by HDAC-independent mechanisms.The ARID domain is involved in stabilizing the mSin3A corepressor complex on DNA. |
Immunogen | Immunogen: A synthesized peptide derived from human BRCAA1 Subcellular Location: Cytoplasmic and Nuclear Tissue Specificity: Highly expressed in the testis and in breast, lung, colon, pancreatic and ovarian cancers. Expressed at low levels in the thymus, prostate and ovary. |
Other Names | [ARID 4B; ARID domain-containing protein 4B; ARID4B; AT rich interactive domain 4B (Rbp1 like); AT rich interactive domain 4B; BCAA; BRCAA 1; BRCAA1; Breast cancer associated antigen 1; Breast cancer associated antigen BRCAA 1; Breast cancer associated antigen BRCAA1; Breast carcinoma associated antigen; DKFZp313M2420; Histone deacetylase complex subunit SAP180; MGC163290; Rb binding protein homolog; RBBP1 L1; RBBP1L1; Rbp 1 like; Rbp1 l1; Rbp1 like; RBP1 like protein; RBP1L; Rbp1l1; Retinoblastoma binding protein 1 like 1; SAP 180; SAP180; SIN3A associated protein 180] |
Gene, Accession # | [BRCAA1], Gene ID: 51742, NCBI: NP_001193723.1, UniProt: Q4LE39 |
Catalog # | MBS9608827 |
Price | $240, $280 |
Order / More Info | BRCAA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |