BRCAA1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBRCAA1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: BRCAA1 antibody detects endogenous levels of total BRCAA1. Function: Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.Subunit Structure: Component of a Sin3A corepressor complex consisting of SIN3A, SAP130, SUDS3/SAP45, SAP180, HDAC1 and HDAC2.Similarity: The C-terminus mediates interaction with mSin3A corepressor complex.The N-terminus is involved in transcriptional repression by HDAC-independent mechanisms.The ARID domain is involved in stabilizing the mSin3A corepressor complex on DNA.
ImmunogenImmunogen: A synthesized peptide derived from human BRCAA1 Subcellular Location: Cytoplasmic and Nuclear Tissue Specificity: Highly expressed in the testis and in breast, lung, colon, pancreatic and ovarian cancers. Expressed at low levels in the thymus, prostate and ovary.
Other Names[ARID 4B; ARID domain-containing protein 4B; ARID4B; AT rich interactive domain 4B (Rbp1 like); AT rich interactive domain 4B; BCAA; BRCAA 1; BRCAA1; Breast cancer associated antigen 1; Breast cancer associated antigen BRCAA 1; Breast cancer associated antigen BRCAA1; Breast carcinoma associated antigen; DKFZp313M2420; Histone deacetylase complex subunit SAP180; MGC163290; Rb binding protein homolog; RBBP1 L1; RBBP1L1; Rbp 1 like; Rbp1 l1; Rbp1 like; RBP1 like protein; RBP1L; Rbp1l1; Retinoblastoma binding protein 1 like 1; SAP 180; SAP180; SIN3A associated protein 180]
Gene, Accession #[BRCAA1], Gene ID: 51742, NCBI: NP_001193723.1, UniProt: Q4LE39
Catalog #MBS9608827
Price$240, $280
Order / More InfoBRCAA1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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