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Antigenic Specificity | Human Interferon regulatory factor 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes. |
Immunogen | Immunogen: Recombinant human Interferon regulatory factor 4 protein(180-451aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-11450 / sc-6059 / sc-28696 |
Other Names | [IRF-4; Lymphocyte-specific interferon regulatory factor; LSIRF; Multiple myeloma oncogene 1; NF-EM5; IRF4; MUM1], [IRF4; IRF4; MUM1; LSIRF; SHEP8; NF-EM5; MUM1; IRF-4; LSIRF] |
Gene, Accession # | [IRF4], Gene ID: 3662, NCBI: NP_001182215.1, UniProt: Q15306 |
Catalog # | MBS1492967 |
Price | $120, $160 |
Order / More Info | Human Interferon regulatory factor 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |