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Antigenic Specificity | FGR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total FGR protein. Fgr is a member of the Src tyrosine kinase family. It has a membrane-associated amino-terminal domain that is highly divergent from other family members, internal conserved SH2 and SH3 domains and a highly conserved carboxy-terminal tyrosine kinase catalytic domain (1,2). Tyrosine 412 is located in the activation loop, and phosphorylation of this residue is critical for the activation of Fgr tyrosine kinase activity. c-Fgr is predominantly expressed in cells of hematopoietic origin including differentiated myeloid cells, NK and B cells (3,4). Fgr plays an important role in the signaling cascade from membrane receptors lacking intrinsic tyrosine kinase activity such as Bcr, FcR, and |
Immunogen | Immunogen Type: Peptide Immunogen Description: A synthetic peptide of human FGR. |
Other Names | [FGR; SRC2; c-fgr; c-src2; p55-Fgr] |
Gene, Accession # | [FGR], Gene ID: 2268, NCBI: NP_001036194.1, UniProt: P09769 |
Catalog # | MBS9410511 |
Price | $255 |
Order / More Info | FGR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |