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Antigenic Specificity | Caspase-8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-8 is a 55 kDa cytosolic protein that is synthesized as an inactive pro-enzyme. Activation of caspase-8 involves a two-step proteolysis: the cleavage of caspase-8 to generate a 43 and a 12 kDa fragment which is further processed to 10 kDa. The p43 is then cleaved to yield p26 and the release of the active site containing p18. |
Immunogen | Immunogen: Synthetic peptide surrounding the cleavage site of human Caspase-8 |
Other Names | [CASP8; MGC78473; CASP-8; MACH; procaspase-8; MCH5; ALPS2B; FLICE; CAP4; EC 3.4.22.61], [CASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; MCH5; CASP-8; FLICE; MACH] |
Gene, Accession # | Gene ID: 841, NCBI: ABX09989 |
Catalog # | MBS841150 |
Price | $150, $290 |
Order / More Info | Caspase-8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |