CD45RB (Leucocyte Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD45RB (Leucocyte Marker) |
| Clone | [BRA-11; BRA-11G] |
| Host Species | Mouse |
| Reactive Species | humandoes not react with rat or rhesus monkey. |
| Isotype | IgG1, kappa |
| Format | CF488 conjugate |
| Size | 0.5 mL |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of |
| Immunogen | Immunogen: Non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V) |
| Other Names | [B220; CD45R; GP180; Leukocyte common antigen (LCA); Loc; Ly-5; Lyt-4; Protein tyrosine phosphatase receptor type C (PTPRC); Receptor-type tyrosine-protein phosphatase C; T200 glycoprotein] |
| Gene, Accession # | [CD45RB], Gene ID: 5788, NCBI: NP_002829.3, UniProt: P08575 |
| Catalog # | MBS4381218 |
| Price | $340 |
| Order / More Info | CD45RB (Leucocyte Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Lim et.al Int. Immunol., 18(2):291-300 (2006). 2. Sedlak et al. Neoplasma 1989: 643, 1989. 3. Sutherland et.al Int. Immunol., 14(8): 953 - 962 (August 1, 2002) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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