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Antigenic Specificity | Kir2.3 |
Clone | [S25-35] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Antibody Microarray (AM) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~45 kDa. No cross-reactivity against Kir2.1 or Kir2.2. Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two tr |
Immunogen | Immunogen: Fusion protein amino acids 390-445 of human Kir2.3 |
Other Names | [Mouse Human Kir2.3 IgG1; Kir2.3 : APC/Cy7; IRK3; HIR; HIRK2; HRK1; KCNJ4; potassium inwardly rectifying channel subfamily J member 4] |
Gene, Accession # | [Kir2.3], Gene ID: 3761, NCBI: NP_004972.1, UniProt: P48050 |
Catalog # | MBS8002830 |
Price | $510 |
Order / More Info | Kir2.3 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Zobel C., et al. (2003) J Physiol. 550: 365-372. 2. Panama B.K., McLerie M., and Lopatin A.N. (2007) Am J Physiol Heart Circ Physiol. 293: H3558-H3567. 3. Munoz V., et al. (2007) Heart Rhythm. 4(4): 487-496. |