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Antigenic Specificity | MAP3K7 |
Clone | [1H6H6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Immunogen | Immunogen: Purified recombinant fusion protein with Thioredoxin (TRX) tag. |
Other Names | [Thioredoxin], [MAP3K7; MAP3K7; CSCF; FMD2; TAK1; MEKK7; TGF1a; TAK1; TGF-beta-activated kinase 1] |
Gene, Accession # | [MAP3K7], Gene ID: 6885, NCBI: NP_663306.1, UniProt: O43318 |
Catalog # | MBS476864 |
Price | $335 |
Order / More Info | MAP3K7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |