ZPK (C-term), 828-859 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | ZPK (C-term), 828-859 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 1.19 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ZPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-859 amino acids from the C-terminal region of human ZPK. ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. |
| Immunogen | n/a |
| Other Names | [Mitogen-activated protein kinase kinase kinase 12; Dual leucine zipper bearing kinase; DLK; Leucine-zipper protein kinase; ZPK; MAPK-upstream kinase; MUK; Mixed lineage kinase; MAP3K12; ZPK] |
| Gene, Accession # | [MAP3K12], Gene ID: 7786, NCBI: NP_001180440.1, UniProt: Q12852 |
| Catalog # | MBS9214125 |
| Price | $165, $370 |
| Order / More Info | ZPK (C-term), 828-859 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Itoh, A., et al., Biochem. Biophys. Res. Commun. 313(3):612-618 (2004). Fukuyama, K., et al., J. Biol. Chem. 275(28):21247-21254 (2000). Reddy, U.R., et al., Oncogene 18(31):4474-4484 (1999). Mata, M., et al., J. Biol. Chem. 271(28):16888-16896 (1996). Hirai, S., et al., Oncogene 12(3):641-650 (1996). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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