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Antigenic Specificity | Phospho-GAB1 (Tyr627) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-GAB1 (Tyr627) antibody detects endogenous levels of GAB1 only when phosphorylated at Tyrosine 627. Description: Grb2-associated binding protein 1 is a member of the IRS-1-like multisubstrate docking protein family. Contains an N-terminal pleckstrin homology (PH) domain and several proline-rich SH3 domain-binding sequences.Function: Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).Subunit Structure: Interacts with GRB2 and with other SH2-containing proteins. Interacts with phosphorylated LAT2. Interacts wit |
Immunogen | Immunogen: A synthesized peptide derived from human GAB1 around the phosphorylation site of Tyrosine 627 Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%) |
Other Names | [Gab 1; GAB1; GAB1_HUMAN; GRB 2 associated binder 1; GRB 2 associated binding protein 1; GRB2 associated binding protein 1 isoform a; GRB2 associated binding protein 1 isoform b; GRB2-associated binder 1; GRB2-associated-binding protein 1; Growth factor receptor bound protein 2-associated protein 1] |
Gene, Accession # | [GAB1], Gene ID: 2549, NCBI: NP_002030.2, UniProt: Q13480 |
Catalog # | MBS9601198 |
Price | $240, $280 |
Order / More Info | Phospho-GAB1 (Tyr627) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |