TLR4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTLR4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionMembers of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses (1-3). TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated ac
ImmunogenImmunogen: Fusion protein to Human TLR4
Other Names[TLR4 Rabbit pab], [TLR4; ARMD10; CD284; TOLL; hToll]
Gene, Accession #Gene ID: 7099, NCBI: NP_003257.1, UniProt: O00206
Catalog #MBS125491
Price$200, $275, $430
Order / More InfoTLR4 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAkira, S. (2003) J Biol Chem 278, 38105-8.Rock, F.L. et al. (1998) Proc. Natl. Acad. Sci. USA 95, 588-593.Poltorak, A. et al. (1998) Science 282, 2085-2088.Chow, J.C. et al. (1999) J. Biol. Chem. 274, 10689-10692.Hoshino, K. et al. (1999) J. Immunol. 162, 3749-3752.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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