Gzma Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGzma
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatfluorescein (FITC) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionAbundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA (By similarity).
ImmunogenImmunogen: Recombinant mouse Granzyme A protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5515
Other Names[Granzyme A (EC:3.4.21.78); Gzma; Ctla-3; Ctla3; Mtsp-1; Autocrine thymic lymphoma granzyme-like serine protease; CTLA-3; Fragmentin-1; T cell-specific serine protease 1; TSP-1], [Gzma; Gzma; Hf; SE1; TSP1; Ctla3; TSP-1; Ctla-3; AW494114; Ctla-3; Ctla3; Mtsp-1; TSP-1]
Gene, Accession #[Gzma], Gene ID: 14938, NCBI: NP_034500.1, UniProt: P11032
Catalog #MBS1491755
Price$160, $235
Order / More InfoGzma Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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