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Antigenic Specificity | ADAM17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The ADAMs (A Disintegrin And Metalloprotease) are multidomain transmembrane proteins. One of the first ADAMs implicated in membrane shedding is ADAM-17, which is shown to release the active form of tumor necrosis factor (TNF)-a from its precursor(PMID:18238782). ADAM17 is also named as CSVP, TACE. The full length protein has 9 glycosylation sites, a signal peptide, propeptide and 2 isoforms produced by alternative splicing.The 120-kDa form of ADAM-17 is expressed more frequently and at higher levels in primary breast carcinomas compared with normal breast tissue(PMID:17438092). This antibody is specific to ADAM17. |
Immunogen | Immunogen: A synthetic peptide of humanADAM17 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [CD156b; MGC71942; TACE; cSVP] |
Gene, Accession # | [ADAM17], Gene ID: 6868, NCBI: NP_003174.3, UniProt: P78536 |
Catalog # | MBS8527353 |
Price | $310 |
Order / More Info | ADAM17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |