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Antigenic Specificity | MEMO1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration. |
Immunogen | Immunogen: Recombinant human Protein MEMO1 protein (1-297AA) |
Other Names | [Protein MEMO1; C21orf19-like protein; Hepatitis C virus NS5A-transactivated protein 7; HCV NS5A-transactivated protein 7; Mediator of ErbB2-driven cell motility 1; Mediator of cell motility 1; Memo-1; MEMO1; C2orf4; MEMO; NS5ATP7; CGI-27] |
Gene, Accession # | [MEMO1], Gene ID: 51072, NCBI: NP_001131074.1, UniProt: Q9Y316 |
Catalog # | MBS7043949 |
Price | $120, $160 |
Order / More Info | MEMO1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |