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Antigenic Specificity | FFAR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FFAR1 antibody detects endogenous levels of total FFAR1. Function: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.Similarity |
Immunogen | Immunogen: A synthesized peptide derived from human FFAR1 Subcellular Location: Cell Membrane Tissue Specificity: Detected in brain and pancreas. Detected in pancreatic beta cells. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog Similarity: Pig (92%), Bovine (83%), Sheep (83%), Rabbit (92%), Dog (92%) |
Other Names | [FFA1R; FFAR 1; Ffar1; FFAR1_HUMAN; Free fatty acid receptor 1; G protein coupled receptor 40; G-protein coupled receptor 40; GPCR40; GPR 40; GPR40] |
Gene, Accession # | [FFAR1], Gene ID: 2864, NCBI: NP_005294.1, UniProt: O14842 |
Catalog # | MBS9608588 |
Price | $240, $280 |
Order / More Info | FFAR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |