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Antigenic Specificity | CASP10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. |
Immunogen | Immunogen: Recombinant human Caspase-10 protein |
Other Names | [Caspase-10; CASP-10; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4; CASP10; MCH4] |
Gene, Accession # | [CASP10], Gene ID: 843, NCBI: NP_001193453.1, UniProt: Q92851 |
Catalog # | MBS7000476 |
Price | $160, $235 |
Order / More Info | CASP10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |