Human CD40 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD40
Clone[hCD40]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
FormatProtein A purified
Size0.5 mg, 1 mg
Concentration1mg/ml in PBS (after reconstitution).
Applicationsn/a
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DescriptionIntroduction: CD40 is part of the TNF-receptor superfamily. CD40 is a necessary mediator for vast range of immune and inflammatory responses together with T cell-dependent immunoglobulin class switching, memory B cell growth, and germinal center formation. The transcription factor AKNA regulates the expression of CD40 and its ligand, which is vital for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is crucial for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is the receptor for TNFSF5/CD40L.
ImmunogenImmunogen: Activated Human B cells. Antibody Properties: Staining antibody. For staining, use 10 ul/1,000,000 cells. Available Conjugates: This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10 ul/106 cells.
Other Namesn/a
Gene, Accession #[CD40], NCBI: ABI49511.1
Catalog #MBS140139
Price$305, $455
Order / More InfoHuman CD40 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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