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Antigenic Specificity | DFF40 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 200 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DFF is composed of two subunits: DFF40/CAD and DFF45/ICAD. Human DFF45 and its mouse homologue ICAD are the inhibitors of DFF40 and CAD, respectively. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40's activation as a nuclease. Activation of DFF40/CAD can lead to DNA fragmentation, a hallmark of apoptosis. DFF40 mRNA is expressed in limited number of human tissues: pancreas, spleen, prostate, and ovary. |
Immunogen | Immunogen: DFF40 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 208 of mouse DFF40 as the immunogen. |
Other Names | [Rabbit DFF40; DFF40; DFF40; DFF-40; DFFB; CPAN; DFF-40; CAD; DFF 40; DFF2; DFF40; DFF-40; DFF 40] |
Gene, Accession # | [DFF40] |
Catalog # | MBS5311143 |
Price | $475 |
Order / More Info | DFF40 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |