Human CD11b Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD11b |
| Clone | [ICRF44] |
| Host Species | Mouse |
| Reactive Species | human, primate, porcine, monkey |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 1.0 mg/ml |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Information: Human CD11b (alpha M integrin) complexes with CD18 (beta 2 integrin) to form the complement receptor type 3 (CR3) heterodimer which binds to ICAM-1, fibrinogen, C3b, and coagulation factor X. CD11b expression is restricted to leukocytes, mainly to myeloid and NK cells. Antibody ICRF44 recognizes the integrin alpha M subunit (CD11b) of about 165 kd. Antibody ICRF44 blocks homotypic neutrophil and monocyte (FMLP induced) aggregation. |
| Immunogen | Immunogen: Human monocytes |
| Other Names | [human CD11b(CR3, Mac-1, integrin aM)/Biotin], [ITGAM; CD11b; CD11B] |
| Gene, Accession # | [CD11b], Gene ID: 397459, NCBI: AAB16869.1 |
| Catalog # | MBS666198 |
| Price | $310 |
| Order / More Info | Human CD11b Antibody from MYBIOSOURCE INC. |
| Product Specific References | V. Mathotra, et al, (1986) Eur J Immunol 16: 1117-1123. B.L. Myones, et al, (1988) J Clin Invest 82: 640-651. Leukocyte Typing IV (W. Knapp, et al, eds.) Oxford University Press, Oxford, (1989) p. 555-558, 560-562. H.R. Petty & R.F. Todd, (1993) J Leuk Biol 54: 492-494. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1588-1590. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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