Integrin beta 3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIntegrin beta 3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, monkey
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentration0.68 mg/mL in antibody stabilization buffer
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionAffinity Purified Integrin beta chain Beta 3 antibody. Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 1-50 on human Integrin Beta 3 subunit protein. Expression: Isoform beta-3A and isoform beta-3C are widely expressed. Isoform beta-3A is specifically expressed in osteoblast cells; isoform beta-3C is specifically expressed in prostate and testis. Volume: 200 uL
Other Names[BDPLT16; BDPLT2; CD61; GP3A; GT; HPA 1; HPA 4; Integrin beta 3 (platelet glycoprotein IIIa antigen CD61); Integrin beta chain beta 3; ITGB 3; NAIT; Platelet fibrinogen receptor, beta subunit; Platelet glycoprotein IIIa; Platelet membrane glycoprotein IIIa; PTP], [ITGB3; ITGB3; GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16; GP3A; GPIIIa]
Gene, Accession #Gene ID: 3690, NCBI: AAB23689.2, UniProt: P05106
Catalog #MBS541911
Price$390
Order / More InfoIntegrin beta 3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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