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Antigenic Specificity | Integrin beta 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 0.68 mg/mL in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Integrin beta chain Beta 3 antibody. Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 1-50 on human Integrin Beta 3 subunit protein. Expression: Isoform beta-3A and isoform beta-3C are widely expressed. Isoform beta-3A is specifically expressed in osteoblast cells; isoform beta-3C is specifically expressed in prostate and testis. Volume: 200 uL |
Other Names | [BDPLT16; BDPLT2; CD61; GP3A; GT; HPA 1; HPA 4; Integrin beta 3 (platelet glycoprotein IIIa antigen CD61); Integrin beta chain beta 3; ITGB 3; NAIT; Platelet fibrinogen receptor, beta subunit; Platelet glycoprotein IIIa; Platelet membrane glycoprotein IIIa; PTP], [ITGB3; ITGB3; GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16; GP3A; GPIIIa] |
Gene, Accession # | Gene ID: 3690, NCBI: AAB23689.2, UniProt: P05106 |
Catalog # | MBS541911 |
Price | $390 |
Order / More Info | Integrin beta 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |