GRB14 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGRB14
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionAdapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
ImmunogenImmunogen: Recombinant Human Growth factor receptor-bound protein 14 protein (294-397AA)
Other Names[Growth factor receptor-bound protein 14; GRB14 adapter protein; GRB14]
Gene, Accession #[GRB14], Gene ID: 2888, NCBI: NP_001290351.1, UniProt: Q14449
Catalog #MBS7105645
Price$160, $235
Order / More InfoGRB14 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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