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Antigenic Specificity | GRB14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal. |
Immunogen | Immunogen: Recombinant Human Growth factor receptor-bound protein 14 protein (294-397AA) |
Other Names | [Growth factor receptor-bound protein 14; GRB14 adapter protein; GRB14] |
Gene, Accession # | [GRB14], Gene ID: 2888, NCBI: NP_001290351.1, UniProt: Q14449 |
Catalog # | MBS7105645 |
Price | $160, $235 |
Order / More Info | GRB14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |