Bcl-2 (Apoptosis& Follicular Lymphoma Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Bcl-2 (Apoptosis& Follicular Lymphoma Marker) |
| Clone | [BCL2/2210R] |
| Host Species | Rabbit |
| Reactive Species | human. |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes a protein of 25-26kDa, identified as the bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative. |
| Immunogen | Immunogen: Recombinant full-length human bcl-2 protein Cellular Localization: Outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes. |
| Other Names | [Apoptosis regulator Bcl-2; B-cell CLL/lymphoma-2] |
| Gene, Accession # | [Bcl-2], Gene ID: 596, NCBI: NP_000624.2, UniProt: P10415 |
| Catalog # | MBS4380205 |
| Price | $190, $340, $340 |
| Order / More Info | Bcl-2 (Apoptosis& Follicular Lymphoma Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Adams, J.M., et al. 1998. The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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