Edit |   |
---|---|
Antigenic Specificity | IRF1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target genes and can act as a transcriptional activator and repressor regulating target genes by binding to an interferon- stimulated response element (ISRE) in their promoters. Its target genes f |
Immunogen | Immunogen: A synthesized peptide derived from human IRF1. Subcellular Localization: Nucleus. Cytoplasm. MYD88-associated IRF1 migrates into the nucleus more efficiently than non-MYD88- associated IRF1. |
Other Names | [Interferon regulatory factor 1; IRF-1; IRF1], [IRF1; IRF1; MAR; IRF-1; IRF-1] |
Gene, Accession # | [IRF1], Gene ID: 3659, NCBI: NP_002189.1, UniProt: P10914 |
Catalog # | MBS179377 |
Price | $160, $340, $340 |
Order / More Info | IRF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |