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Antigenic Specificity | ITGB6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:17158881). |
Immunogen | Immunogen: Recombinant Human Integrin beta-6 protein (451-586AA) |
Other Names | [Integrin beta-6; ITGB6] |
Gene, Accession # | [ITGB6], Gene ID: 3694, NCBI: NP_000879.2, UniProt: P18564 |
Catalog # | MBS7106968 |
Price | $160, $235 |
Order / More Info | ITGB6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |